Jonathan Chait in the New Republic says it:
The Egyptian populace seems almost totally united in opposition to Mubarak, with the only significant support coming from those in Mubarak's pay. The opposition has all the nationalist and religious legitimacy it needs. At this point Obama needs to forcefully cut Mubarak loose. The only delay, I would hope, is his slowness to respond to events, a trait he has consistently displayed since the campaign. Sometimes that caution has served him well, but here it hasn't. If Obama does not act soon it will be a black mark.